Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check out reviews of Santo Antonio hotels guests love
The Vine
10/10 Excellent
" Truly Impressive Stay!
From the moment we arrived, we were blown away by the stunning architecture — the design is both elegant and inviting. The location couldn’t be more perfect, close to everything yet peaceful and relaxing. Our room (and the entire hotel) was spotless, with every detail carefully maintained.
Highly recommended and would absolutely stay again!"
"Absolutely gorgeous and clean facilities, pools, rooms, and dining. I highly recommend the half board option, the food and service was impeccable. The staff was gracious enough to upgrade our room as a celebration for a HUGE job promotion I had just received (and the reason for my trip). Can’t recommend this place enough. The demographic is a bit older but my fiance and I expected this. The sites poolside were breathtaking and there were plenty of places to sit. Great wine selection and the menu at the main restaurant changed nightly making it so we never got bored. 10/10 Cliff Bay! "
"This hotel is really amazing I feel like the pictures don't do it justice the pictures are nice that's why I picked this hotel but staying here was a completely different experience and feeling the staff where great especially the staff in the premium lounge I don't noticed I booked for that package but it's a must you get daily breakfast and a evening snack free drinks and it's expensive it's own deck you get access to the spa which is the most discreet and exclusive spa I've been to that line made our trip magical you the spa is down a huge stair case into a hidden oasis in the middle of the hotel completely amazing I can't say enough the hotel it's self is away from tourist attractions bit we wanted that rent a car be cautious they like to drive very fast just book this hotel you will not regret it , the price is high but the experience is well worth it "
"We had a lovely stay at Dom Pedro Madeira. The room was very nice and clean. Staff was very helpful and made our stay even better. Breakfast buffet was excellent too. The hotel is close to the airport which is a bonus. "
If you need the flexibility to change your plans to Santo Antonio, most accommodations offer refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Santo Antonio if I want a vacation home instead of a hotel?
If you want a good alternative to a hotel, review our selection of 18 vacation homes. You can also book one of 54 apartments or 20 villas.
What will the weather in Santo Antonio be like during my vacation?
August and July are typically the warmest months in Santo Antonio when the average temp is 67°F. February and March are the coldest months when the average temperature is 56°F. December and November are the months with the most rain.
Why should I book my Santo Antonio hotel through Hotels.com?
There are lots of reasons to book your Santo Antonio trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.
Find out more about Santo Antonio
Find out more about Santo Antonio
If you're looking for a place to get away, look no further than Santo Antonio. Whether you're planning to stay for a night or for the week, the area around Santo Antonio has accommodations to fit every need. Search for hotels in Santo Antonio with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Santo Antonio hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Santo Antonio hotel deals are here with our lowest price guarantee.