Photo by Erick Huling

Hotels in Southwest Oklahoma

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Where to stay in Southwest Oklahoma?

Exterior
AmericInn by Wyndham Sayre
AmericInn by Wyndham Sayre
2.5 star property
8.6 out of 10, Excellent, (541)
The price is $88
$101 total
includes taxes & fees
Jan 1 - Jan 2, 2026
AmericInn by Wyndham Sayre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Southwest Oklahoma, OK

Showing deals for:Dec 12 - Dec 14

Image gallery for Fairfield Inn & Suites by Marriott Chickasha

Reception

Fairfield Inn & Suites by Marriott Chickasha

2.5 star property
Chickasha
9.0/10Wonderful (158 reviews)
15% off
$97 nightly
Price is $228
Total with taxes and fees
Fairfield Inn & Suites by Marriott Chickasha

Check out pet-friendly hotels in Southwest Oklahoma

Exterior
AmericInn by Wyndham Sayre

AmericInn by Wyndham Sayre

2.5 star property
Sayre
8.6 out of 10, Excellent, (541)
The price is $88
$101 total
includes taxes & fees
Jan 1 - Jan 2, 2026
AmericInn by Wyndham Sayre
View all properties

You may also like hotels with hot tubs in Southwest Oklahoma

Exterior
AmericInn by Wyndham Sayre

AmericInn by Wyndham Sayre

2.5 star property
Sayre
8.6 out of 10, Excellent, (541)
The price is $88
$101 total
includes taxes & fees
Jan 1 - Jan 2, 2026
AmericInn by Wyndham Sayre
View all properties

You can also stay at hotels with a pool in Southwest Oklahoma

Exterior
AmericInn by Wyndham Sayre

AmericInn by Wyndham Sayre

2.5 star property
Sayre
8.6 out of 10, Excellent, (541)
The price is $88
$101 total
includes taxes & fees
Jan 1 - Jan 2, 2026
AmericInn by Wyndham Sayre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top landmarks in Central United States

Sunset landscape with a full moon in Wichita Mountains National Wildlife Refuge

Wichita Mountains Wildlife Refuge

4.6/5 (287 reviews)
Wichita Mountains Wildlife Refuge is 11.2 mi (18.1 km) from central Indiahoma, why not stop by during your stay. Want to stretch your legs some more? Head to Wichita Mountains National Wildlife Refuge, located nearby.
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The Narrows. #hikes #hiking #oklahoma #wichita mountains
Photo by David Morring
Open Photo by David Morring

Wichita Mountains

4.6/5 (165 reviews)
If you want to stretch your legs and breathe in some fresh mountain air, head out to Wichita Mountains for a bird's-eye view of Lawton.
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Learn more about Southwest Oklahoma

Southwest Oklahoma is well-known for its casinos and university life, featuring attractions such as Caddo Lake and Wichita Mountains. Visitors highlight this family-friendly city's museums while sights include Wichita Mountains Wildlife Refuge and Medicine Park Aquarium & Natural Sciences Center.

See all hotels in Southwest Oklahoma
These two precariously balanced boulders are a must see in The Wichita Mountains Wildlife Refuge. Park at Sunset Pool and head west on the trail. You won't be disappointed.
Photo by Erick Huling
Open Photo by Erick Huling

Check out reviews of Southwest Oklahoma hotels guests love

MySuites Lawton

MySuites Lawton

10/10 Excellent
"All the above"
Tammy 1-night trip
Posted 5 days ago
MySuites Lawton

Frequently asked questions

Why should I book my Southwest Oklahoma hotel through Hotels.com?
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