Hotel Museo Spa Casa Santo Domingo
Luxury hotel with 2 restaurants, near Casa Santo Domingo Museum
Photo gallery for Hotel Museo Spa Casa Santo Domingo





In the heart of Antigua's historical district, Hotel Museo Spa Casa Santo Domingo offers a luxurious retreat. Unwind at the poolside bar, indulge in a rejuvenating spa treatment, or explore the nearby Casa Santo Domingo Museum and Central Park. With two on-site restaurants serving Fusion cuisine and activities like ziplining available, you'll experience an unforgettable stay.
VIP Access
Reviews
9.2 out of 10
Wonderful
Popular amenities
The current price is $238
$303 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Why we love this property

Spa and wellness getaway
A full-service spa offers aromatherapy, massages, and body treatments daily. The sauna, hot tub, and garden create perfect relaxation spaces.

Garden-view luxury
Step into this boutique hotel's enchanting garden with local artist showcases. The garden-view restaurant offers luxury dining in a historical district.

Fusion and Italian flavors
Sample 2 restaurants offering Fusion and Italian cuisines with garden views. Full breakfast is available at this hotel with 2 bars.
Room options
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Showing 13 of 13 rooms
View all photos for Superior Suite, 1 King Bed, Jetted Tub (All rooms are different)

Superior Suite, 1 King Bed, Jetted Tub (All rooms are different)
Highlights
Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Separate bedroom
Hair dryer
View all photos for Standard Spa Living (All rooms are different)

Standard Spa Living (All rooms are different)
9.2 out of 10
Wonderful
(11 reviews)
Highlights
Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Private bathroom
Hair dryer
View all photos for Superior Suite Spa Living (All rooms are different)

Superior Suite Spa Living (All rooms are different)
10.0 out of 10
Exceptional
(2 reviews)
Highlights
Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Private bathroom
Hair dryer
View all photos for Standard Room (All rooms are different)

Standard Room (All rooms are different)
9.0 out of 10
Wonderful
(33 reviews)
Highlights
Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Private bathroom
Hair dryer
View all photos for Standard Room, 1 King Bed, Jetted Tub (All rooms are different)

Standard Room, 1 King Bed, Jetted Tub (All rooms are different)
10.0 out of 10
Exceptional
(5 reviews)
Highlights
Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Hair dryer
Private bathroom
View all photos for Deluxe Room (All rooms are different)

Deluxe Room (All rooms are different)
9.8 out of 10
Exceptional
(12 reviews)
Highlights
Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Private bathroom
Hair dryer
View all photos for Executive Suite (All rooms are different)

Executive Suite (All rooms are different)
Highlights
Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Separate bedroom
Private bathroom
View all photos for Exclusive Suite, 1 King Bed (All rooms are different)

Exclusive Suite, 1 King Bed (All rooms are different)
Highlights
Fireplace
Private hot tub
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Separate bedroom
View all photos for Executive Suite, 1 King Bed (All rooms are different)

Executive Suite, 1 King Bed (All rooms are different)
10.0 out of 10
Exceptional
(1 review)
Highlights
Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Separate bedroom
Private bathroom
View all photos for Junior Suite (All rooms are different)

Junior Suite (All rooms are different)
9.6 out of 10
Exceptional
(4 reviews)
Highlights
Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Private bathroom
Hair dryer
View all photos for Deluxe Suite (All rooms are different)

Deluxe Suite (All rooms are different)
10.0 out of 10
Exceptional
(5 reviews)
Highlights
Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Separate bedroom
Premium bedding
Pillowtop bed
View all photos for Suite (All rooms are different)

Suite (All rooms are different)
10.0 out of 10
Exceptional
(3 reviews)
Highlights
Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Separate bedroom
Private bathroom
View all photos for Superior Suite, Jetted Tub (All rooms are different)

Superior Suite, Jetted Tub (All rooms are different)
9.4 out of 10
Exceptional
(3 reviews)
Highlights
Fireplace
Air conditioning
Connecting rooms available
Smart TV
Pillow menu
Premium bedding
Hair dryer
Private bathroom
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includes taxes & fees
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About the neighborhood

3a Calle Oriente No 28 A, Antigua Guatemala, Sacatepequez, 3001
About this property
Hotel Museo Spa Casa Santo Domingo
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