Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau hotel with spa and indoor pool

Choose dates to view prices

Where to?

Dates

December 2025

8

January 2026

Exterior - Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG (Cape Girardeau)

Indoor pool, open 8 AM to 11 PM, sun loungers - Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG (Cape Girardeau)

Free breakfast - Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG (Cape Girardeau)

Premium bedding, down comforters, pillowtop beds, in-room safe - Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG (Cape Girardeau)

Located in a rural setting, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers a warm welcome with free breakfast and an inviting indoor pool. Relax at the onsite spa or take some time to unwind by the swimming pool with sun loungers. With dry cleaning/laundry services, luggage storage, and helpful staff previous guests rave about.

Exceptional

Popular amenities

Connecting rooms available
Non-smoking
Laundry facilities

Main amenities (12)

Daily housekeeping
Full-service spa
Indoor pool
Fitness center
Business center
24-hour front desk
Front-desk safe
Vending machine
Laundry service
Self-serve laundry
Conference space
Meeting room

Feel at home (6)

Microwave
Connecting/adjoining rooms available
Private bathroom
Separate sitting area
Premium TV channels
Daily housekeeping

$107 total

includes taxes & fees

Dec 22 - Dec 23

Room options

Check availability for these dates

Tonight

Dec 8 - Dec 9

Tomorrow

Dec 9 - Dec 10

All rooms

1 bed

2 beds

Showing 9 of 9 rooms

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Very good

Highlights

Separate sitting area

Air conditioning

Connecting rooms available

Mini-fridge

Flat-screen TV

Pillow menu

Down duvet

Premium bedding

37 sq m
Sleeps 6
2 Queen Beds

Suite, 1 King Bed, Accessible (Roll-In Shower)

Exceptional

Highlights

Separate sitting area

Air conditioning

Connecting rooms available

Mini-fridge

Flat-screen TV

Pillow menu

Down duvet

Premium bedding

Sleeps 2
1 King Bed

Suite, 1 King Bed

Exceptional

Highlights

Separate sitting area

Air conditioning

Connecting rooms available

Mini-fridge

Flat-screen TV

Pillow menu

Down duvet

Premium bedding

Sleeps 2
1 King Bed

Suite, 2 Queen Beds

Exceptional

Highlights

Separate sitting area

Air conditioning

Connecting rooms available

Mini-fridge

Flat-screen TV

Pillow menu

Down duvet

Premium bedding

Sleeps 6
2 Queen Beds

Suite, 2 Queen Beds, Accessible (Mobility)

Exceptional

Highlights

Separate sitting area

Air conditioning

Connecting rooms available

Mini-fridge

Flat-screen TV

Pillow menu

Down duvet

Premium bedding

37 sq m
Sleeps 6
2 Queen Beds

Standard Room, 1 Queen Bed

Wonderful

Highlights

Separate sitting area

Air conditioning

Connecting rooms available

Mini-fridge

Flat-screen TV

Pillow menu

Premium bedding

Down duvet

37 sq m
Sleeps 2
1 Queen Bed

Standard Room

Very good

Highlights

Separate sitting area

Air conditioning

Connecting rooms available

Mini-fridge

Flat-screen TV

Pillow menu

Down duvet

Premium bedding

37 sq m
Sleeps 2
1 King Bed

Suite, 1 Bedroom (Feature)

Exceptional

Highlights

Separate sitting area

Air conditioning

Connecting rooms available

Mini-fridge

Flat-screen TV

Pillow menu

Premium bedding

Down duvet

Sleeps 2
1 Queen Bed

Suite, 1 King Bed, Accessible (Mobility)

Exceptional

Highlights

Separate sitting area

Air conditioning

Connecting rooms available

Mini-fridge

Flat-screen TV

Pillow menu

Down duvet

Premium bedding

Sleeps 2
1 King Bed

Similar properties

Pool
Free breakfast
Pet friendly
Free parking

$112 total

includes taxes & fees

Dec 21 - Dec 22

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About the neighborhood

3253 William Street, Cape Girardeau, MO, 63701

What's nearby

Saint Francis Medical Center - 6 min walk - 0.6 km
Southeast Missouri Hospital - 5 min drive - 5.3 km
Southeast Missouri State University - 6 min drive - 6.3 km
Isle Casino Cape Girardeau - 8 min drive - 9.1 km
Show Me Center - 9 min drive - 9.1 km

Getting around

Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive
Cairo, IL (CIR-Cairo Regional) - 38 min drive

Restaurants

‪Chick-fil-A - ‬7 min walk
‪Rhodes - ‬20 min walk
‪McDonald's - ‬10 min walk
‪White Castle - ‬10 min walk
‪Wings Etc. - ‬9 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

When visiting Cape Girardeau, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a great choice to consider. Guests can take a dip in the indoor pool or visit the fitness center for a workout. Fellow travelers say great things about the helpful staff and breakfast.

At a glance

Hotel size

- 102 rooms
- Arranged over 4 floors

Arriving/Leaving

- Check-in start time: 3:00 PM; Check-in end time: anytime
- Contactless check-in available
- Minimum check-in age: 21
- Check-out time is 11 AM
- Contactless check-out available

Special check-in instructions

- Front desk staff will greet guests on arrival at the property
- Information provided by the property may be translated using automated translation tools

Required at check-in

- Credit card, debit card, or cash deposit required for incidental charges
- Government-issued photo ID may be required
- Minimum check-in age is 21

Children

- No cribs (infant beds)

Pets

- Pets not allowed

Internet

- Free WiFi and wired internet access in public areas
- Free WiFi and wired internet access in rooms

Parking

- Free onsite self parking
- Wheelchair-accessible parking on site

Other information

- Smoke-free property

Property amenities

Food and drink

Free breakfast

Working away

Business center
Meeting room
Conference space (118 square feet)

Services

24-hour front desk
Dry cleaning/laundry services
Free newspapers in lobby
Luggage storage
Porter/bellhop
Pool loungers

Facilities

1 building/tower
Safe-deposit box at front desk
Fitness center
An indoor pool
Full-service spa
Banquet hall

Accessibility

Braille/raised signage
Wheelchair-accessible path of travel
Wheelchair-accessible parking
Assistive listening devices available
Wheelchair-accessible path to elevator
Closed captioned TV
Visual fire alarm
Well-lit path to entrance

Room amenities

Be entertained

52-inch flat-screen TV
Premium cable channels

Home comfort

Air conditioning (climate-controlled)
Coffee/tea maker
Iron/ironing board

Sleep well

Pillow menu
Down comforter
Premium bedding
Pillowtop mattress

What to enjoy

Separate sitting area

Freshen up

Private bathroom
Free toiletries
Hair dryer
Towels
Toilet paper

Stay connected

Desk
Free WiFi and wired internet
Free local calls

Food and drink

Mini-fridge
Microwave

More

Daily housekeeping
In-room safe
Connecting/adjoining rooms available

Special features

Spa

Guests can indulge in a pampering treatment at the hotel's full-service spa.

Fees & policies

Pool, spa, & gym (if applicable)

Pool access available from 8 AM to 11 PM

Policies

The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.

Guests can rest easy knowing there's a smoke detector on site.

This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

This property accepts credit cards. Cash is not accepted.

Credit cards accepted: Visa, Mastercard, American Express, Discover, Diners Club, JCB International, Carte Blanche

Cashless transactions are available.

This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

Also known as

Holiday Inn Express Cape Girardeau I-55

Holiday Inn Express Hotel Cape Girardeau I-55

Holiday Inn Hotel I-55

Holiday Inn Express Hotel Suites Cape Girardeau I 55

Inn Express Cape Girarau I55

Holiday Inn Express Hotel Suites Cape Girardeau I 55

Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offer free cancellation for a full refund?

Yes, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG does have fully refundable room rates available to book on our site. If you’ve booked a fully refundable room rate, this can be cancelled up to a few days before check-in depending on the property's cancellation policy. Just make sure to check this property's cancellation policy for the exact terms and conditions.