Hotels in Byron

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Check prices for these dates

Tonight
Dec 1 - Dec 2
Tomorrow
Dec 2 - Dec 3
This weekend
Dec 5 - Dec 7
Next weekend
Dec 12 - Dec 14

Where to stay in Byron?

Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
7.2 out of 10, Good, (1027)
The price is $68
$78 total
includes taxes & fees
Dec 2 - Dec 3
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top landmarks in Byron

High Point Shopping Center

If you like shopping, take time out to go to High Point Shopping Center when in Byron. Splash some more cash at Byron Town Square.
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Valley View Park

Valley View Park is worth a visit, located 0.4 mi (0.6 km) from central Byron.
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Check out reviews of Byron hotels guests love

Hampton Inn Rochester-South

Hampton Inn Rochester-South

10/10 Excellent
"We had a wonderful stay!"
Sarah 2-night trip
Posted 1 day ago
Hampton Inn Rochester-South

Frequently asked questions

What hotels do travelers recommend in Byron?
Guests like Kahler Grand Hotel, Kahler Inn and Suites - Mayo Clinic Area and Hampton Inn Rochester-South.
Can I book refundable accommodations in Byron?
If you're looking for the flexibility to change your plans to Byron, most properties provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Byron be like during my vacation?
July and August are typically the warmest months in Byron when the average temp is 67°F. January and February are the coldest months when the average temperature is 21°F. June and May are the months with the most rain.
Why should I book my Byron hotel with Hotels.com?
There are lots of reasons to book your Byron trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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