Hotels in O Brien

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Tonight
Oct 14 - Oct 15
Tomorrow
Oct 15 - Oct 16
This weekend
Oct 17 - Oct 19
Next weekend
Oct 24 - Oct 26

Where to stay in O Brien?

Breakfast area
Hampton Inn & Suites Alachua I-75
Hampton Inn & Suites Alachua I-75
2.5 star property
9.4 out of 10, Exceptional, (460)
The price is $114
$128 total
includes taxes & fees
Oct 20 - Oct 21
Hampton Inn & Suites Alachua I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

O Brien is well-known for its attractions such as Suwannee River and Ichetucknee River.

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An amazing state Park 2 hours drive from Orlando. Swimming and snorkeling in this crystal clear water is allowed and i really recommend to do it! 🐟🐢
Photo by Dr__Vlad
Open Photo by Dr__Vlad

Check out reviews of O Brien hotels guests love

Postcard Cabins Gilchrist Springs

Postcard Cabins Gilchrist Springs

10/10 Excellent
"Amazing cabins, clean and perfect for a weekend getaway "
Maurizio 2-night trip
Posted 1 day ago
Postcard Cabins Gilchrist Springs

Frequently asked questions

Can I book refundable hotels in O Brien?
If you want the flexibility to change your travel plans to O Brien, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in O Brien if I want a vacation home instead of a traditional hotel?
You'll find 6 vacation homes on our site.
What will the weather in O Brien be like during my vacation?
July and August are typically the warmest months in O Brien when the average temp is 80°F. January and February are the coldest months when the average temperature is 58°F. June and August are the months with the most rain.
Why should I book my O Brien hotel with Hotels.com?
There are lots of reasons to book your O Brien trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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